Journal: ACS Medicinal Chemistry Letters

Article Title: Generation of Broad-Spectrum Antifungal Drug Candidates from the Natural Product Compound Aureobasidin A

doi: 10.1021/acsmedchemlett.5b00029

Figure Lengend Snippet: In Vitro Activity of Compound 15 against Filamentous Fungi

Article Snippet: Table 2 MIC (μg/mL) Organism ATCC # Cmpd 20 Am B a Aspergillus fumigatus 20435 1 0.25 Aspergillus fumigatus MYA-32626 2 0.25 Aspergillus flavus 204304 1 0.25 Aspergillus flavus 22546 2 0.25 Aspergillus flavus 64025 1 0.5 Aspergillus candidus 13686 0.008 0.03 Aspergillus clavatus 10058 0.03 0.004 Aspergillus niger 16888 0.125 0.03 Aspergillus niger 64028 0.03 0.015 Aspergillus ochraceus 96919 0.25 0.25 Emericella nidulans 96921 0.125 1 Fusarium oxysporum 48112 >64 1 Rhizopus oryzae 11886 >64 0.03 Sporothrix schenkii 14284 >64 0.5 Trichophyton mentagrophytes MYA-4439 0.5 0.06 Trichophyton mentagrophytes 28185 1 0.06 Trichophyton rubrum MYA-4438 2 0.03 Open in a separate window a Am B, amphothericin B.

Techniques: In Vitro, Activity Assay

Journal:

Article Title: Evaluation of a New Cellulose Sponge-Tipped Swab for Microbiological Sampling: a Laboratory and Clinical Investigation

doi: 10.1128/JCM.41.5.1894-1900.2003

Figure Lengend Snippet: Viability of a selection of anaerobic and microaerophilic species suspended in BHI held in swabs in transport medium a

Article Snippet: Viability of a selection of aerobically growing species suspended in BH1 and held in swabs in dry tubes a table ft1 table-wrap mode="anchored" t5 TABLE 2. caption a7 Strain and temp (°C) Cellswab + Amies Cellswab + Stuart Copan + Amies Orion + Stuart No. of days with ≥10% of the original no. of CFU detected Original no. of CFU detected No. of days with ≥10% of the original no. of CFU detected Original no. of CFU detected No. of days with ≥10% of the original no. of CFU detected Original no. of CFU detected No. of days with ≥10% of the original no. of CFU detected Original no. of CFU detected Actinomyces israelii ATCC 10049 18 44 15 17 23 ± 1 2 4 4 4 4 ≥14 ≥14 ≥14 ≥14 Bacteroides vulgatus clinical strain 300 500 150 200 23 ± 1 1 4 1 1 4 2 4 2 2 Campylobacter jejuni NCTC 143483 5 × 10 3 5 × 10 3 5 × 10 3 5 × 10 3 23 ± 1 0 1 0 0 4 4 4 4 4 Clostridium difficile ATCC 17858 150 250 250 300 23 ± 1 ≥14 ≥14 ≥14 ≥14 4 ≥14 b ≥14 b ≥14 ≥14 Clostridium perfringens ATCC 13124 30 50 16 5 23 ± 1 4 2 1 1 4 ≥14 ≥14 7 ≥14 Eubacterium lentum clinical strain 2 × 10 3 2 × 10 3 2 × 10 3 2 × 10 3 23 ± 1 7 ≥14 7 7 4 ≥14 ≥14 ≥14 ≥14 Neisseria gonorrhoeae ATCC 49226 2 × 10 3 2 × 10 3 2 × 10 3 10 3 23 ± 1 1 2 0 0 4 0 4 0 1 Peptostreptococcus anaerobius clinical strain 10 3 10 3 600 600 23 ± 1 1 1 1 0 4 4 4 4 2 Prevotella intermedia ATCC 33563 1.4 × 10 3 3.3 × 10 3 1.8 × 10 3 3.2 × 10 3 23 ± 1 0 0 0 0 4 2 2 2 2 Propionibacterium propionius ATCC 14157 5 × 10 3 5 × 10 3 5 × 10 3 5 × 10 3 23 ± 1 7 7 7 1 4 ≥14 ≥14 ≥14 ≥14 Open in a separate window a See Table for details. b Increase in CFU (growth in the swab) was observed.

Techniques: Selection